| Mode | Volume assist control |
| Tidal volume | 8 mL/kg predicted body weight (This setting should not need to be titrated.) |
| Inspiratory flow rate | 60–80 L/min |
| Respiratory rate | Start at 8-10 breaths/min; adjust to allow full expiration |
| PEEP | 0 cm H2O (some may use PEEP ≤5 cm H2O) |
| FiO2 | Start at 40%; adjust for SpO2 ≥ 88% |