Gout
NSAID's (4-10 days)
- CAUTION - elderly, renal failure, HTN, PUD, liver disease, coumadin
- Indomethacin
- Naprosyn
- Suldinac
Steroids
- CAUTION - joint infections, diabetics
- Prednisone
- 40 mg PO qdaily x 3 days and then taper over 10-14 days
Colchicine (0.6 mg)
- CAUTION - lower dose in elderly and renal or hepatic insufficieny
- CAUTION - lower dose in patients on CYP3A4 inhibitors (HAART, anti-fungals, abx) or P-gp inhibitors (cyclosporine)
- 2 tabs and then 1 tab q1-q3 hours until sx's improve or N/V/D
DIET
- Avoid beer, animal protein