BRUE - brief, resolved unexplained event

• Infant < 1 year with ≥1 of the following
• cyanosis or pallor
• absent, decreased, or irregular breathing
• marked change in tone (hyper- or hypotonia
• altered level of responsiveness

Low risk patients

• age > 60 days
• gestational age ≥32 weeks and postconceptional age ≥45 weeks
• no prior BRUE
• duration of BRUE < 1 minute
• no CPR by trained medical provider
• no concerning historical features/physical examination findings (e.g. FH of sudden cardiac death, or subtle non-diagnostic social, feeding, or respiratory problems)

Consider

• Low risk
  
• pertussis testing and an ECG
• briefly monitor patients with continuous pulse oximetry and serial observations
• High risk
• Obtain CBC, CXR, ECHO, EEG
• Initiate home monitoring
• Prescribe acid suppression therapy or anti-convulsants.
• Admit for monitoring